From the Journals

Metformin Ineffective for COVID Recovery, Trial Finds

Researchers found metformin did not significantly shorten COVID-19 symptom duration in low-risk outpatients, though it was safe and well tolerated.

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6 Key Takeaways

  • 1

    Metformin did not significantly reduce COVID-19 symptom duration.

  • 2

    Study conducted on 2991 participants aged 30 and older.

  • 3

    Median recovery time: 9 days for metformin, 10 for placebo.

  • 4

    Safety events were rare, with no cases of lactic acidosis.

  • 5

    Majority of participants had 2 or more COVID-19 vaccine doses.

  • 6

    Need for further studies noted for validation of findings.

Original Source(s)

Metformin Ineffective for COVID Recovery, Trial Finds

Researchers found metformin did not significantly shorten COVID-19 symptom duration in low-risk outpatients, though it was safe and well tolerated.

  • by Kathryn Wighton

  • July 17, 2025

  • 3 min

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