From the Journals

TAVI Reduces GI Lesions, Bleeding in Heyde

Six months post-TAVI, GI lesion counts in Heyde syndrome patients fell by 68% — with 55% of typical angiodysplasias disappearing, offering a promising dual benefit for aortic stenosis and GI bleeding management.

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  • 1

    TAVI led to a significant reduction in the mean number of vascular lesions per patient from 6.4 to 2.0 post-TAVI.

  • 2

    Angiogenesis markers, including VEGF and angiopoietin-2, decreased significantly after TAVI, suggesting a potential mechanism for the reduction in lesion count.

  • 3

    TAVI may offer benefits beyond AS management, potentially reducing GI bleeding risk associated with angiodysplasia in Heyde syndrome.

  • 4

    Patients with multiple valvular disease experienced no complete resolution of lesions post-TAVI, while 75% of those with isolated AS saw improvement.

  • 5

    Paravalvular leakage post-TAVI was associated with a higher likelihood of persistent lesions.

Original Source(s)

TAVI Reduces GI Lesions, Bleeding in Heyde

Six months post-TAVI, GI lesion counts in Heyde syndrome patients fell by 68% — with 55% of typical angiodysplasias disappearing, offering a promising dual benefit for aortic stenosis and GI bleeding management.

  • by Kathryn Wighton

  • November 5, 2024

  • 2 min

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