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From the Journals

A Two-Biomarker Signal for Alzheimer’s Disease

Dual plasma biomarkers may improve identification of established Alzheimer’s disease and signal faster decline

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  • 1

    The combination of eMTBR-tau243 and p-tau217 improves Alzheimer’s diagnosis.

  • 2

    Study included 572 patients with cognitive symptoms.

  • 3

    Biomarkers help distinguish patients with significant tau pathology.

  • 4

    Higher eMTBR-tau243 levels predict faster cognitive decline.

  • 5

    The study supports a two-step testing strategy for better diagnostic precision.

  • 6

    Findings may influence therapy choices for Alzheimer’s patients.

  • 7

    Further studies are necessary for broader clinical validation.

Original Source(s)

A Two-Biomarker Signal for Alzheimer’s Disease

  • by Henry Thomas

  • March 30, 2026

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