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PFAS Bioaccumulation: The Biology of Forever

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  • February 23, 2026

  • 20 min

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  • 1

    PFAS interact uniquely with proteins and phospholipids.

  • 2

    Traditional risk assessment models for persistent organic pollutants are inadequate for PFAS.

  • 3

    Research focuses on bioaccumulation and exposure from drinking water.

  • 4

    Unidentified organofluorine compounds pose analysis challenges.

  • 5

    Long-term exposure assessment is crucial for evaluating health impacts.

  • 6

    Advanced analytical techniques, especially high-resolution mass spectrometry, are necessary.

  • 7

    The transformation of PFAS precursors into persistent compounds complicates risk understanding.

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