From the Journals

Hypertension: Biomarkers Clarify Heart Failure Risk

Cardiac biomarkers help stratify heart failure risk among patients with prediabetes and hypertension.

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    Hypertensive adults with prediabetes and myocardial injury have a 4.20-fold risk of heart failure.

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    Biomarkers: hs-cTnI ≥6 ng/L (men), ≥4 ng/L (women), NT-proBNP ≥125 pg/mL.

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    Study based on 8,234 participants.

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    Key findings: Prediabetes without myocardial injury shows no excess risk.

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    Observational study design limits causal conclusions.

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    Follow-up median: 3.2 years, resulting in 122 heart failure events.

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    Importance of biomarker monitoring emphasized.

Original Source(s)

Hypertension: Biomarkers Clarify Heart Failure Risk

Cardiac biomarkers help stratify heart failure risk among patients with prediabetes and hypertension.

  • by Kathryn Wighton

  • February 23, 2026

  • 4 min

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