Raman Tool Opens the Door to Continuous Vaccine Manufacturing
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By
February 2, 2026
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3 min
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1
Purdue University and Merck & Co developed a Raman spectroscopy tool.
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2
Tool enables real-time monitoring of viral particles.
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3
Traditional testing methods are time-consuming and inefficient.
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4
New tool reduces quality control time to 30 seconds.
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5
It captures undamaged viral samples for accurate analysis.
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6
Future improvements will focus on portable systems for in-line monitoring.
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7
This technology enhances vaccine manufacturing efficiency and product quality.
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Researchers at Purdue University and Merck & Co have developed a novel Raman spectroscopy-based tool aimed at real-time monitoring of viral particles during vaccine manufacturing processes. This advancement addresses a significant bottleneck by enabling continuous quality control, as traditional methods require time-consuming sample removal and testing. The tool allows analysis within 30 seconds, ensuring undamaged viral samples and improving manufacturing efficiency. Future work will focus on integrating portable Raman systems into commercial lines to further enhance monitoring capabilities in complex media.
-
1
Purdue University and Merck & Co developed a Raman spectroscopy tool.
-
2
Tool enables real-time monitoring of viral particles.
-
3
Traditional testing methods are time-consuming and inefficient.
-
4
New tool reduces quality control time to 30 seconds.
-
5
It captures undamaged viral samples for accurate analysis.
-
6
Future improvements will focus on portable systems for in-line monitoring.
-
7
This technology enhances vaccine manufacturing efficiency and product quality.
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