What's Heart Disease Got to Do With It?
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By
January 27, 2026
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3 min
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1
Mental health conditions increase acute coronary syndrome risk.
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2
PTSD doubles the risk of acute myocardial infarction.
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3
Anxiety and sleep disorders have significant associations.
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4
Heterogeneity exists in the studies reviewed.
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5
Integrating mental health into cardiac care may improve outcomes.
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6
Limited evidence quality for some conditions.
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7
Sleep quality impacts cardiovascular health.
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A systematic review in JAMA Psychiatry reveals that mental health conditions, notably depression, anxiety, PTSD, and sleep disorders, significantly elevate the risk of acute coronary syndrome (ACS) events. Analyzing data from 25 studies with over 22 million participants, researchers found PTSD linked to a 2.73 times greater risk of acute myocardial infarction (AMI). The study suggests integrating mental health management into cardiovascular care could enhance patient outcomes but acknowledges limitations due to study heterogeneity and potential biases.
-
1
Mental health conditions increase acute coronary syndrome risk.
-
2
PTSD doubles the risk of acute myocardial infarction.
-
3
Anxiety and sleep disorders have significant associations.
-
4
Heterogeneity exists in the studies reviewed.
-
5
Integrating mental health into cardiac care may improve outcomes.
-
6
Limited evidence quality for some conditions.
-
7
Sleep quality impacts cardiovascular health.
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