From the Journals

Refining Vancomycin Use in Early CDI

A modified dosing approach could reshape recurrence prevention strategies.

Share

  • 1

    C. difficile infection has high morbidity and mortality.

  • 2

    TAPER-V trial tested a vancomycin pulse-and-taper regimen.

  • 3

    74% probability of 4-week regimen preventing recurrence.

  • 4

    Conducted in 12 Canadian hospitals with 265 patients.

  • 5

    Recurrence rates were 15% for pulse-and-taper; 18% for placebo.

  • 6

    Future trials needed for optimizing therapy.

Original Source(s)

Refining Vancomycin Use in Early CDI

A modified dosing approach could reshape recurrence prevention strategies.

  • by Julia Cipriano, MS, CMPP

  • March 4, 2026

  • 2 min

Related Content

Sepsis Antibiotic Timing Shows Physician Divide

Emergency department physicians differ in how quickly they initiate antibiotics for suspected sepsis.

Top 10 States to Practice Infectious Diseases

The following list highlights the states that offer the most favorable conditions for infectious disease physicians.