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Mapping the Metabolism of Plant Mixtures 

A multilayer networking workflow reveals mixture-dependent metabolism of kratom alkaloids A multilayer networking workflow reveals mixture-dependent metabolism of kratom alkaloids 

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  • March 10, 2026

  • 3 min

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  • 1

    New workflow combines high-resolution mass spectrometry and multilayer molecular networking.

  • 2

    Focuses on kratom (Mitragyna speciosa), a plant with numerous alkaloids.

  • 3

    Enables analysis of metabolic fates of whole plant extracts.

  • 4

    Identifies both phase I and II metabolites.

  • 5

    Reveals how complex mixtures affect metabolism.

  • 6

    Takes days instead of years to analyze.

  • 7

    Potential applications in dietary supplements and herbal medicines.

Original Source(s)

Mapping the Metabolism of Plant Mixtures 

A multilayer networking workflow reveals mixture-dependent metabolism of kratom alkaloids A multilayer networking workflow reveals mixture-dependent metabolism of kratom alkaloids 

  • March 10, 2026

  • 3 min

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