From the Journals

Mediterranean Metabolite Signature Tied to Lower RA, Study

66-metabolite signature explains 22.4% of the Mediterranean diet–RA relationship.

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8 Key Takeaways

  • 1

    Higher Mediterranean diet adherence correlates with lower RA incidence.

  • 2

    32% reduction in RA risk for top diet quintile.

  • 3

    66 metabolites identified in metabolic signature.

  • 4

    Metabolic signature explains 2

  • 5

    4% of diet-RA association.

  • 6

    Participants aged 37-73 provided dietary data and plasma samples.

  • 7

    Cox models adjusted for various confounding factors.

  • 8

    Study limited by single-timepoint metabolomics and demographic homogeneity.

Original Source(s)

Mediterranean Metabolite Signature Tied to Lower RA, Study

66-metabolite signature explains 22.4% of the Mediterranean diet–RA relationship.

  • by Stanley Gajete

  • October 21, 2025

  • 4 min

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