Fetal Growth Extremes Linked to MS Risk
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By
January 15, 2026
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3 min
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1
Maternal diabetes more than doubles MS risk for offspring.
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2
Study analyzed data from over a million births.
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3
Preterm birth and maternal hypertensive disorders not linked to MS.
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4
Fetal growth extremes showed significant associations with risk.
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5
Methodology involved Cox proportional hazards models.
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6
Limitations included underreporting of maternal health issues.
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7
Findings emphasize importance of the perinatal period.
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A large population-based study in Norway has revealed that offspring exposed to maternal diabetes during pregnancy face more than double the risk of developing multiple sclerosis (MS) in adulthood. Analyzing data from over one million births, researchers examined the impact of factors such as preterm birth and fetal growth on MS risk. The study highlighted that while preterm birth and maternal hypertensive disorders were not linked to increased MS risk, maternal diabetes and birth weight extremes did show significant associations, necessitating a focus on perinatal influences on MS risk.
-
1
Maternal diabetes more than doubles MS risk for offspring.
-
2
Study analyzed data from over a million births.
-
3
Preterm birth and maternal hypertensive disorders not linked to MS.
-
4
Fetal growth extremes showed significant associations with risk.
-
5
Methodology involved Cox proportional hazards models.
-
6
Limitations included underreporting of maternal health issues.
-
7
Findings emphasize importance of the perinatal period.
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