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1
EOC cells in ascites exist mainly as compact spheroids.
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2
These spheroids often include mesothelial cells.
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3
Mesothelial cells aid in cancer tissue invasion.
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4
Presence of malignant cells is linked to shorter progression-free survival.
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5
Ascites is an active environment promoting metastasis.
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6
Potential therapeutic target: disrupt cancer-mesothelial interactions.
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7
Evaluate both malignant and nonmalignant cells for disease progression.
Original Source(s)
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