New Workflow for Precise Bile Acid Profiling and Multi-Omics Discovery
November 27, 2025
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2 min
7 Key Takeaways
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1
Developed a next-gen LC-MS/MS workflow for bile acid analysis.
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2
Overcomes analytical challenges associated with bile complexity.
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3
Utilizes ZenoTOF 8600 system for high specificity and speed.
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4
Employs electron-activated dissociation for better isomer differentiation.
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5
Takes under 10 minutes for result delivery.
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6
Promises to advance research in metabolomics and gut health.
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7
Aims to enable early diagnostics and personalized therapies.
A team of scientists has developed a next-generation LC-MS/MS workflow using the ZenoTOF 8600 system to advance bile acid analysis. This innovative approach addresses challenges related to the complexity of bile acids, offering high specificity and speed in profiling, thereby aiding diagnostics and therapeutics. Utilizing electron-activated dissociation (EAD), the new technique distinguishes isomeric bile acids and reduces chemical noise. This breakthrough facilitates rapid analysis, which could significantly impact future research in metabolomics and gut health.
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