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The Baby Steps of Infant Immunity

LC-MS profiling shows rapid establishment of systemic immunity in infants 

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  • March 4, 2026

  • 2 min

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  • 1

    Newborns produce antibodies within weeks, not months.

  • 2

    Study used LC-MS-based Fab profiling.

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    Maternal IgG1 present at birth; IgA1 almost absent.

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    By 7-11 weeks, infants show new IgA1 and IgG1 production.

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    No evidence of milk IgA entering bloodstream.

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    IgA1 acts primarily at mucosal surfaces.

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    Implications for neonatal immune development and vaccination strategies.

Original Source(s)

The Baby Steps of Infant Immunity

LC-MS profiling shows rapid establishment of systemic immunity in infants 

  • March 4, 2026

  • 2 min

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