Feature

Collagen: Emerging Importance in Dry Eye Therapy 

Advances in corneal science are reshaping how we understand – and potentially treat – dry eye disease

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  • 1

    Collagen is essential for corneal structure and epithelial cell function.

  • 2

    In dry eye disease, collagen disruption leads to increased inflammation and epithelial instability.

  • 3

    Collagen mimetic peptides can restore collagen architecture and enhance repair.

  • 4

    The ST-100 trial showed significant improvements in ocular surface health.

  • 5

    CMPs may represent a novel first-line treatment option for various dry eye subtypes.

Original Source(s)

Collagen: Emerging Importance in Dry Eye Therapy 

Advances in corneal science are reshaping how we understand – and potentially treat – dry eye disease

  • by Jay S. Pepose

  • March 10, 2026

  • 8 min

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