Dana-Farber's Research News highlights new studies by faculty members, featuring immune checkpoint therapy targeting LAG-3, the dependency of small cell lung cancer on POU2F3, and novel MET mutations that could guide targeted treatments in various cancers. A study emphasizes the utility of the Breast Cancer Index for enhancing therapy decisions in hormone receptor-positive breast cancer. Moreover, research on hypofractionated radiation post-mastectomy reveals quality-of-life impacts, while circulating tumor DNA signals promise for cancer progression monitoring across malignancies.
1. Dana-Farber showcases faculty's recent research on cancer therapies. 2. LAG-3 is targeted for advanced melanoma therapy alongside PD-1 blockade. 3. Small cell lung cancer dependency on POU2F3 offers therapeutic insights. 4. The Breast Cancer Index is key for adjuvant treatment decisions in HR+ breast cancer. 5. Hypofractionated radiation shows promise in postmastectomy outcomes. 6. Circulating tumor DNA tests offer a new biomarker for recurrence in Merkel cell carcinoma. 7. Research highlights the need for precision oncology applications.
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